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Broccoli Compound Helps Destroy Breast Cancer Cells

New research suggests that a specific compound called indole-3-carbinol (I3C) found in cruciferous vegetables (broccoli, cauliflower, Brussels sprouts, cabbage, kale, etc.) may be especially helpful in inhibiting breast cancer development. Researchers at the University of Leicester looked at the effect of I3C on four different types of breast cancer cells. Previous studies have shown that foods rich in indoles may help to kill breast cancer cells by diminishing the expression of the epidermal growth factor receptor that protects cancer cells. This study found that I3C helped to reduce these receptors in three of the four types of breast cancer cells. Consuming cruciferous vegetables daily may significantly lower breast cancer risk and increase survival.

Moiseeva EP, Heukers R, Manson MM. EGFR and Src are involved in indole-3-carbinol-induced death and cell cycle arrest of human breast cancer cells. Carcinogenesis 2007. Feb;28:435-45.

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